Aims & Learning Objectives:
Aims: To provide an understanding of the molecular basis of antibody function and the principles of their application in immunochemical techniques. To provide an understanding of the significance of protein:protein interactions. To provide an understanding of the three-dimensional structure of protein molecules that play an important role in the immune system.
After taking this course the student should be able to:
* understand the molecular basis for antigen:antibody interaction
* appreciate the role of antibody as a component of the immune system
* understand the basis of specific immunochemical methods and their applications.
Content:
Overview of the immune system and the biological role of antibodies, structure of an antibody molecule and its relationship to antigen-binding and effector functions, principles of immunochemical techniques, protein:protein interactions and their importance for the function of oligomeric proteins, principles of protein folding and understanding of the three-dimensional structure of immunological relevant proteins.
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