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Department of Chemical Engineering, Unit Catalogue 2007/08


CE10079 Biology & bio-processes

Credits: 6
Level: Certificate
Semester: 1
Assessment: EX 100%
Requisites:
Aims: The course assumes that the majority of students will have done some biology at GCSE but none at A-level. It is therefore an introduction to aspects of biology and fermentation that enable us to exploit micro- organism systems in order to develop useful products and processes (e.g. enzymes, alcohol, effluent treatment, pharmaceuticals and food stuffs).
Learning Outcomes:
After successfully completing this unit the student should:
* Have an understanding of the importance of biological systems in the modern process industries;
* Be aware of the different types and classifications of organisms which exist in the microbial kingdom;
*Understand the basic chemistry, structure and function of the main classes of biochemicals;
* Have a basic understanding of the role of DNA and genetics in regulating biological activity, and how DNA can be manipulated to produce "new" processes and products;
* Be aware of the major internal structures in microbial cells and their functions; understand that enzymes are responsible for the catalysis of biochemical reactions, and how these reactions are regulated;
* Have a basic knowledge of at least two commercial bio-processes.
Skills:
This course is designed to provide a knowledge base and industrial awareness of bioprocesses, to act as a foundation for design and synthesis in subsequent courses. This knowledge is taught and assessed.
Content:

* Introduction to biochemical processes and the types of product that are currently produced on industrial scale.
* Classification of organisms within the microbial kingdom and the types of compound which they require for growth or which they can produce as products.
* Basic chemistry, structure and function of these biochemical compounds.
* The role of DNA and genetics in regulation of metabolic and microbial activity, and its significance in modern biotechnology.
* Basic structure of microbial cells, including intra-cellular structures and their biological function.
*The role of enzymes in regulation and catalysis of biochemical reactions.
* Introduction to metabolic pathways and the coupling of degradative and synthetic reactions.
* Case studies of selected commercial bioprocesses, e.g. sewage treatment, alcoholic beverage production, cheese production, antibiotic production, food processing etc.