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Department of Chemistry, Unit Catalogue 2007/08


CH20161 Drug properties 2

Credits: 6
Level: Intermediate
Semester: 2
Assessment: EX100
Requisites:
Aims: The Unit will provide an introduction to the properties of drugs and some of the key aspects of medicinal chemistry which need to be considered by chemists involved in synthesising new drug molecules.
Learning Outcomes:
After studying the Unit, students should be able to:
* provide examples of how drugs are able to interact with DNA/RNA/ enzyme receptors;
* provide examples of drug metabolism;
* recognise the importance of molecular modelling to the drug discovery process.
Skills:
Numeracy (F, A), Problem solving (T, F, A), Scientific writing (F, A), Independent working (F), Group working (F).
Content:
Case studies of enzyme inhibition and the mechanism of drug action and drug molecules with DNA and RNA. Natural products as drugs. Neurotransmitters and their agonist and antagonists. Receptor interactions and molecular modelling.