Department of Chemistry, Unit Catalogue 2008/09 |
CH40141 Topics in catalysis for organic synthesis |
| Credits: 3 |
| Level: Masters |
| Semester: 1 |
| Assessment: EX 100% |
| Requisites: |
| Before taking this unit you must take CH20149 or take CH20150 and in taking this unit you cannot take CH30141 and while taking this unit you must take CH30071 or take CH30128 |
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Aims: To describe and demonstrate recent techniques in the application of catalysis to the synthesis of organic molecules. To illustrate how either metal-complexes or organocatalysts can be applied to the asymmetric synthesis of valuable intermediates.
Learning Outcomes: After studying the Unit, students should be able to: * Describe a range of catalytic systems for achieving important synthetic transformations * Account for the importance of asymmetric catalysis in organic synthesis * Integrate catalytic techniques with retrosynthetic analysis to introduce new stereocentres to organic molecules * Extend the principles encountered in the course to critical discussion of recent and potential advances in asymmetric catalysis * Solve synthetic problems using the techniques introduced including the application of techniques to unseen situations. Skills: Problem solving (T, F, A), Scientific writing (F, A), Independent working (F). Content: The development of chiral Lewis acids and their application in a range of synthetic transformations. A complementary approach to asymmetric synthesis using organocatalysis. Enantioselective palladium and rhodium catalysed carbon-carbon bond forming processes. A review of recent developments in the area of catalysis applied to organic synthesis. The application of catalysis to the synthesis of complex molecules. |