Dr Giordano Pula
Profile
Research
- Vascular Biology: Paracrine Regulation of Endothelial Cell Motility and Angiogenesis, Regenerative Angiogenesis, Redox Regulation of Cell Physiology and Angiogenic Responses, Endothelial Progenitor Cell Biology.
- Thrombosis and Haemostasis: Autocrine and Paracrine Regulation of Platelet Activity, Redox Regulation of Platelet Responses and Thrombus Formation, Platelet Intracellular Signaling and Protein Kinase Cascades, Integrin regulation.
Current funding
- Wellcome Trust, Multiuser Equipment Grant (2012). Cell Sorting Flow Cytometry for the Study of Live Cell, Cell Surface and Intracellular Processes, (ZR-W0258A).
- University of Bath Research Studentship (2012). Endothelial progenitor cells and biomaterials: a powerful synergy for innovative regenerative medicine.
- BBSRC Project Grant (2012). Paracrine regulation of endothelial cell motility and angiogenesis by deoxyribose-1-phosphate. (BB/J002690/1).
Publications
Vara, D., Campanella, M. and Pula, G., 2013. The novel NOX inhibitor 2-acetylphenothiazine impairs collagen-dependent thrombus formation in a GPVI-dependent manner. British Journal of Pharmacology, 168 (1), pp. 212-224.
Vara, D. S., Campanella, M., Canobbio, I., Dunn, W. B., Pizzorno, G., Hirano, M. and Pula, G., 2013. Autocrine amplification of integrin αIIbβ3 activation and platelet adhesive responses by deoxyribose-1-phosphate. Thrombosis and Haemostasis, 109 (6), pp. 1108-1119.
Pula, G., Garonna, E., Dunn, W. B., Hirano, M., Pizzorno, G., Campanella, M., Schwartz, E. L., El Kouni, M. H. and Wheeler-Jones, C. P. D., 2010. Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate. Arteriosclerosis, thrombosis, and vascular biology, 30 (12), pp. 2631-2638.
Prokopi, M., Pula, G., Mayr, U., Devue, C., Gallagher, J., Xiao, Q., Boulanger, C. M., Westwood, N., Urbich, C., Willeit, J., Steiner, M., Breuss, J., Xu, Q., Kiechl, S. and Mayr, M., 2009. Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Blood, 114 (3), pp. 723-732.
Pula, G., Mayr, U., Evans, C., Prokopi, M., Vara, D. S., Yin, X., Astroulakis, Z., Xiao, Q., Hill, J., Xu, Q. and Mayr, M., 2009. Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures. Circulation Research, 104 (1), pp. 32-40.
Pula, G., Perera, S., Prokopi, M., Sidibe, A., Boulanger, C. M. and Mayr, M., 2008. Proteomic analysis of secretory proteins and vesicles in vascular research. Proteomics Clinical Applications, 2 (6), pp. 882-891.
Pula, G. and Poole, A. W., 2008. Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrinα2β1. Platelets, 19 (3), pp. 199-210.
Pula, G. and Krause, M., 2008. Role of Ena/VASP Proteins in Homeostasis and Disease. Handbook of experimental pharmacology, 186 (1), pp. 39-65.
