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Biomedical Modelling

We develop and analyse mathematical and computational models to understand how physical forces and mechanical properties influence biological systems.

Our research combines biology, physics and applied mathematics to investigate how tissues and fluids interact across scales - from cells to organs. By linking theoretical and computational models with experimental and imaging data, we aim to uncover the mechanical principles that underpin normal physiology and disease.

Mathematical approaches

We use methods from solid and fluid mechanics, continuum mechanics, and numerical simulation to describe deformation, flow and stress in biological tissues and organs. Fluid–structure interaction models and finite element techniques allow us to represent complex geometries and material behaviours within computational frameworks.

Applications

Our work addresses a wide range of physiological systems, including blood flow, eye fluid dynamics, heart and arterial mechanics, and the development of bone and soft tissues. We also study fluid-solid interactions in joints and organs, and the mechanics of microorganism movement.

This research contributes to understanding healthy and pathological function, with potential applications in medical diagnostics, device design and regenerative medicine.

Staff working in this area