The 500 MHz Bruker NMR spectrometer with a Prodigy cryoprobe is the centrepiece of the DReaM Facility. Using the InsightMR flowprobe and software, the homogeneous reaction mixture is pumped directly from the reaction vessel into the flow cell in the spectrometer, analysed in flow and then returned to the reaction vessel.
The Prodigy cryoprobe is able to observe nuclei with Larmor frequencies of 15N and above. Routinely, 1H, 19F, 31P and 13C experiments are used.
The spectrometer is able to maintain reaction temperatures between -20 and 80 °C.