SL20009: Enzymology (BB20018)
[Page last updated: 26 October 2023]
| Academic Year: | 2023/24 |
| Owning Department/School: | Department of Life Sciences |
| Credits: | 6 [equivalent to 12 CATS credits] |
| Notional Study Hours: | 120 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
- Semester 2
|
| Assessment Summary: | EX 80%, PR 20% |
| Assessment Detail: |
- BB20018 Practical (PR 20%)
- BB20018 Examination (EX 80%)
|
| Supplementary Assessment: |
- Like-for-like reassessment (where allowed by programme regulations)
|
| Requisites: |
Before taking this module you must ( take BB10003 AND take 1 MODULE FROM {BB10004, BB10121} ) OR take BB10263
|
| Learning Outcomes: |
After taking this course the student should be able to:
* describe the relationship between protein structure, ligand binding and enzyme catalysis;
* explain how enzymes achieve their high catalytic rates;
* explain steady-state kinetics of enzyme-catalysed reactions, the nature of reversible inhibition, and the effects of temperature and pH;
* describe and carry out the requirements of reliable enzyme assays;
* explain allosteric regulation in the control of enzymes;
* describe the organisation of cellular enzymes into multienzyme complexes and multifunctional enzymes;
* describe the role of isoenzymes in cellular regulation, development and differentiation, and their application to diagnosis of disease;
* describe and explain the role of coenzymes in enzyme catalysis.
|
| Aims: | To provide a fundamental understanding of enzymes as catalysts, at a physio-chemical level, and to relate these molecular properties to their cellular functions.
|
| Skills: | Learning and studying T/F/A, Written communication T/F/A, Numeracy & computation T/F/A, Laboratory skills T/F, Information technology T/F, Problem solving T/F, Information handling & retrieval T/F/A, Working independently T/F, Career preparation T/F.
|
| Content: | Ligand binding; steady-state kinetics; inhibition; effects of temperature and pH; principles of enzyme assay; theories of catalysis; allostery; isoenzymes, multienzyme complexes; coenzyme chemistry.
|
| Course availability: |
SL20009 is Compulsory on the following courses:
Department of Chemistry
- USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Year long work placement (Year 2)
- USSC-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 2)
- USSC-AAM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 2)
- USSC-AKM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Professional Placement (Year 2)
- USSC-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 2)
- USSC-AAM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 2)
- USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 2)
- USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 2)
- USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Professional Placement (Year 2)
Department of Life Sciences
- USSL-AFB01 : BSc(Hons) Biochemistry (Year 2)
- USSL-AKB01 : BSc(Hons) Biochemistry with Professional Placement (Year 2)
- USSL-AFM01 : MBiochem(Hons) Biochemistry (Year 2)
- USSL-AKM01 : MBiochem(Hons) Biochemistry with Professional Placement (Year 2)
SL20009 is Optional on the following courses:
Department of Chemistry
- USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Year long work placement (Year 2)
- USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 2)
- USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 2)
Department of Life Sciences
- USSL-AFB03 : BSc(Hons) Biomedical Sciences (Year 2)
- USSL-AKB03 : BSc(Hons) Biomedical Sciences with Professional Placement (Year 2)
- USSL-AFM03 : MBioMed(Hons) Biomedical Sciences (Year 2)
- USSL-AKM03 : MBioMed(Hons) Biomedical Sciences with Professional Placement (Year 2)
|
Notes: - This unit catalogue is applicable for the 2023/24 academic year only. Students continuing their studies into 2024/25 and beyond should not assume that this unit will be available in future years in the format displayed here for 2023/24.
- Courses and units are subject to change in accordance with normal University procedures.
- Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
- Find out more about these and other important University terms and conditions here.
|
