Description:
| Aims: To provide an in-depth understanding of the relationship between DNA synthesis, damage & repair mechanisms in relation to cell cycle and apoptosis. Also provides an understanding of how disruption of normal cellular function leads to disease processes, especially cancer.
Learning Outcomes: After taking this course the student should be able to:
* give a detailed account of DNA replication, damage and repair in prokaryotic and eukaryotic systems;
* describe and explain the cross talk between cell cycle and apoptosis in relation to oncogenesis;
* explain the rationale behind tumour therapy, either conventional approaches of radio/chemotherapy or newer approaches of genetherapy, immunotherapy, angiotherapy etc.
Skills: Learning and studying T/F/A, Written communication T/F/A, Laboratory skills T/F, Information technology T/F, Information handling & retrieval T/F/A, Working independently T/F.
Content: DNA replication and repair in relation to disease. Role of cell cycle and apoptosis in oncogenesis. Various modes of cancer therapy.
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