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Department of Biology & Biochemistry, Unit Catalogue 2010/11


BB30055: Genes & genomes

Click here for further information Credits: 6
Click here for further information Level: Honours
Click here for further information Period: This unit is available in...
Semester 1
Click here for further information Assessment: EX 100%
Click here for further informationSupplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Click here for further information Requisites: Before taking this unit you must take BB10007 and (take BB20023 or take BB20110)
Click here for further information Description: Aims:
To provide an advanced study of genome structure and expression in eukaryotes.

Learning Outcomes:
After taking this course the student should be able to:
* describe and explain the complexities of gene regulation and the various stages at which expression is regulated;
* describe and explain the ways in which mRNA differs from the primary transcript;
* Explain how to use genome structural information to distinguish between individuals;
* devise a strategy for the identification and mapping of genes.

Skills:
Learning and studying T/F/A, Written communication T/F/A, Information handling & retrieval T/F/A, Working independently T/F.

Content:
Genome structure and mapping (genetic & physical). Repetitive DNA, its origins and use in DNA fingerprinting. Assembly of the eukaryotic RNA synthetic machinery and its regulation by transcription factors. Chromatin remodelling in transcription. RNA splicing, editing and other modifications and their control.
NB. Programmes and units are subject to change at any time, in accordance with normal University procedures.