Department of Biology & Biochemistry, Unit Catalogue 2010/11 |
BB40102: Molecular mechanisms of disease |
 Credits:
| 6 |
| Level:
| Masters |
| Period: | This unit is available in... |
| Semester 1 |
| Assessment:
| CW 100% |
| Supplementary Assessment: | Like-for-like reassessment (where allowed by programme regulations) |
| Requisites:
| In taking this unit you cannot take BB40085 or take BB40118 or take BB40124 and before taking this unit you must take BB20024 and take BB10003 or you must have taken suitable degree units from another University. |
| Description:
| Aims: To describe how a defect at the level of the gene results in an observed disease phenotype. To show how such patients can be treated with modern molecular medicine. Learning Outcomes: After taking this course the student should be able to: * explain the common themes of genetic disorders, and how they relate to the overall phenotype; * explain the principles of tools involved in diagnosis and treatment of the disorders. Skills: Learning and studying T/F/A, Written communication T/F/A, Oral communication T/F/A, Information handling & retrieval T/F/A, Working independently T/F/A. Content: Diseases: diabetes, glycogen storage diseases, hyperbilirubinaemia, familial hypercholesterolaemia, fibroblast growth factor receptors and skeletal dysplasia. Diagnosis and treatment: PCR/cloning, antibody engineering, gene therapy, gene targeting in the mouse, mouse models for human disease. |