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Department of Biology & Biochemistry, Unit Catalogue 2010/11


BB40164: Modern methods of researching neurodegeneration

Click here for further information Credits: 6
Click here for further information Level: Masters
Click here for further information Period: This unit is available in...
Semester 2
Click here for further information Assessment: CW 100%
Click here for further informationSupplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Click here for further information Requisites: Before taking this unit you must (take BB20028 or take BB20099) and take BB30044
Click here for further information Description: Aims:
This unit is aimed at highlighting the different techniques that can/could be used to investigate neurodegenerative disorders and allow the student to develop a working knowledge of standard models of a variety of human neurodegenerative diseases. The models will include, cell, molecular and animal models.

Learning Outcomes:
After taking this course the student should be able to:
* Describe at least six major strategies for investigating neurodegenerative diseases.
* Critically evaluate research papers on subjects related to research on neurodegenerative diseases
* Distinguish between classes of neurodegenerative disorders in terms of the kinds of models available for researching them.

Skills:
Learning and studying T/F/A, Written communication T/F/A, Information handling & retrieval T/F/A, Working independently T/F/A, Oral communication T/F/A.

Content:
Techniques used for the study of neurodegenerative diseases: Transgenic approaches, polymerisation assays, behavioural tests, protein structure studies, in vivo and in vitro models of neuronal death (animal and cell models), cell signalling cascades and apoptosis, electrophysiological approaches and analysis of sectioned tissues from patients.
NB. Programmes and units are subject to change at any time, in accordance with normal University procedures.