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Department of Biology & Biochemistry, Unit Catalogue 2011/12


BB40184: Cell biology of metastasis

Click here for further information Credits: 6
Click here for further information Level: Masters UG & PG (FHEQ level 7)
Click here for further information Period: Semester 1
Click here for further information Assessment: CW 100%
Click here for further information Supplementary Assessment: Reassessment not allowed
Click here for further information Requisites: Before taking this unit you must take BB20023 and take BB20160
Click here for further information Description: Aims:
To provide an overview of our current understanding of key cellular processes such as the maintenance of epithelial cell polarity and the control of cell migration. To describe how defects in the regulation of these process contribute to the metastatic behaviour of cancer cells. To summarise current methods used to study these processes and the advantages and limitations of these approaches.

Learning Outcomes:
After taking this course the students should be able to:
1. Describe the regulation of key cellular processes such as the formation and maintenance of epithelial cell polarity and the regulation of cell migration.
2. Explain how defects in the normal regulation these process might contribute to metastatic behaviour.
3. Assess the merits and limitations of the different experimental approaches used to study these processes.

Skills:
Learning and studying (T/F/A), information handling and retrieval (T/F/A), working independently (T/F), written communication (T/F/A) and oral communication (T/F/A).

Content:
Formation and maintenance of epithelial cell polarity, epithelial to mesenchymal transition, cell migration.
Click here for further informationProgramme availability:

BB40184 is Compulsory on the following programmes:

Department of Biology & Biochemistry
  • TSBB-AFM07 : MSc Developmental Biology (Full-time) - Year 1

BB40184 is Optional on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB02 : BSc (hons) Biochemistry (Full-time) - Year 3
  • USBB-AKB06 : BSc (hons) Biochemistry with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
  • USBB-AFB05 : BSc (hons) Molecular and Cellular Biology (Full-time) - Year 3
  • USBB-AKB08 : BSc (hons) Molecular and Cellular Biology with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
  • USBB-ANM02 : MBiochem (hons) Biochemistry (Full-time with Thin Sandwich Placements) - Year 4
  • USBB-AKM05 : MBiol (hons) Molecular and Cellular Biology (Full-time with Thick Sandwich Placement) - Year 4
  • RSBB-AFM07 : Integrated PhD Postgenomic Biosciences (Biosciences Route) (Full-time) - Year 1
  • TSBB-AFM03 : MRes Biosciences (Full-time) - Year 1
  • TSBB-AFM06 : MSc Biosciences (Full-time) - Year 1
  • TSBB-AFM09 : MSc Medical Biosciences (Full-time) - Year 1

NB. Programmes and units are subject to change at any time, in accordance with normal University procedures.