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CH40037: Synthesis of medicinal compounds

Follow this link for further information on academic years Academic Year: 2019/0
Further information on owning departmentsOwning Department/School: Department of Chemistry
Further information on credits Credits: 3      [equivalent to 6 CATS credits]
Further information on notional study hours Notional Study Hours: 60
Further information on unit levels Level: Masters UG & PG (FHEQ level 7)
Further information on teaching periods Period:
Semester 2
Further information on unit assessment Assessment Summary: EX 100%
Further information on unit assessment Assessment Detail:
  • Examination (EX 100%)
Further information on supplementary assessment Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: In taking this module you cannot take CH30037
Before taking this module you must take CH20149 OR take CH20150 or equivalent from another university.
Further information on descriptions Description: Aims:
To introduce and illustrate how advanced synthetic organic chemistry is used in the preparation of medicinally valuable compounds.

Learning Outcomes:
After studying this Unit, students should be able to:
* Apply knowledge of protecting group strategy in the synthesis of complex biological molecules.
* Apply knowledge of retrosynthetic analysis to the forward design of biologically active molecules.
* Define reagents and strategies for the assembly of stereochemically defined molecules.
* Design rational analogues, or modified compounds from given starting chemicals.
* Critically assess contemporary organic synthetic strategy and methodology.
* Develop an understanding for the rationale and purpose of complex target-orientated organic synthesis.

Skills:
Problem solving (T, F, A), Scientific writing (F, A), Independent working (F).

Content:
The unit is designed to give a sound knowledge of contemporary organic synthesis set within the context of synthesising biologically active molecules. The unit will set in context retrosynthetic analysis, protecting group strategy and modern methodology by means of total synthesis.
Further information on programme availabilityProgramme availability:

CH40037 is Compulsory on the following programmes:

Department of Chemistry
  • USCH-AAM06 : MChem(Hons) Chemistry for Drug Discovery with Study year abroad (Year 4)
  • USCH-AKM03 : MChem(Hons) Chemistry for Drug Discovery with Industrial Placement (Year 4)

CH40037 is Optional on the following programmes:

Department of Chemistry
  • USCH-AAM03 : MChem(Hons) Chemistry with Study year abroad (Year 4)
  • USCH-AKM02 : MChem(Hons) Chemistry with Industrial Placement (Year 4)
  • USCH-AFM07 : MSci(Hons) Chemistry with Management (Year 4)
  • USCH-AKM07 : MSci(Hons) Chemistry with Management with Industrial Placement (Year 5)
Programmes in Natural Sciences
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Professional Placement (Year 5)

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