Department of Pharmacy & Pharmacology, Unit Catalogue 2011/12 |
|
 Credits:
| 3 |
| Level:
| Intermediate (FHEQ level 5) |
| Period: |
Semester 1 |
| Assessment:
| EX100 |
| Supplementary Assessment: | Like-for-like reassessment (where allowed by programme regulations) |
| Requisites:
| |
| Description:
| Aims: * To familiarise the student with the major families of receptors and the components of intracellular signalling pathways from receptor to cell nucleus. * To introduce the major cellular and humoral components of the immune system and to illustrate its role in health and disease. * To provide a basic understanding of the techniques used to detect protein expression. * To illustrate clinical cases through problem-based learning. Learning Outcomes: After taking this unit, the student will be able to: * List a variety of receptor families and outline their mechanism of activation and links to intracellular pathways; * Describe the physiological role of the immune system; * Apply knowledge of these pathways and systems to explain the underlying mechanisms which cause disease; * Explain the uses and limitations of antibodies in the laboratory and in the diagnosis and treatment of disease. Skills: Scientific and practical skills (T/F/A) Study skills, handling information, working with others (T/F) Problem solving (T/F). Content: Receptor families, second messenger systems, protein kinases and their phosphorylation targets. The innate and adaptive immune system - antibodies, T and B lymphocytes, antigen presenting cells and the MHC, effector functions, tolerance and autoimmunity. Use of protein detection assays and antibodies as laboratory, diagnostic and therapeutic agents. Problem based learning applied to relevant clinical case studies. |
| Programme availability: |
PA20292 is a Designated Essential Unit on the following programmes:Department of Pharmacy & Pharmacology
PA20292 is Compulsory on the following programmes:Department of Pharmacy & Pharmacology
PA20292 is Optional on the following programmes:Programmes in Natural Sciences
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