|
 Academic Year:
| 2012/3 |
| Owning Department/School:
| Department of Biology & Biochemistry |
| Credits:
| 6 |
| Level:
| Masters UG & PG (FHEQ level 7) |
| Period: |
Semester 1 |
| Assessment:
| CW 20%, EX 80% |
| Supplementary Assessment: | BB40188 Re-assessment coursework (where allowed by programme regulations) |
| Requisites:
| |
| Description:
| Aims: To introduce the process of transcription in prokaryotes. To provide an understanding of ribosome structure and mRNA translation in both prokaryotes and eukaryotes. To advance knowledge of protein folding and the intracellular pathways of folding and post-translational modification. To provide an in-depth understanding of the various pathways of intracellular and extracellular protein turnover. To provide students with a critical and integrated overview of the key processes controlling the production and turnover of cellular proteins, informed by current research. Learning Outcomes: After taking this course the student should be able to: * demonstrate knowledge of how bacterial gene expression is regulated at the transcriptional level and the process of translation; * critically evaluate our current understanding of the processes involved in protein folding; * demonstrate a thorough understanding of the pathways involved in protein turnover, and analyse its significance in cellular processes; * analyse the strengths and limitations for current predictive methods for protein structure. Skills: Learning and studying T/F/A, Written communication T/F/A, Information handling & retrieval T/F/A, Working independently T/F. Content: Prokaryotic transcription Translation Protein Folding Posttranslational modification Protein Turnover Computational approaches to the prediction of protein folding (practical). |
| Programme availability: |
BB40188 is Optional on the following programmes:Department of Biology & Biochemistry
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