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CH40216: Topics in organic chemistry I for natural sciences

Follow this link for further information on academic years Academic Year: 2012/3
Further information on owning departmentsOwning Department/School: Department of Chemistry
Further information on credits Credits: 3
Further information on unit levels Level: Masters UG & PG (FHEQ level 7)
Further information on teaching periods Period: Semester 1
Further information on unit assessment Assessment: EX100
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this unit you must take CH20149 or take CH20150 and in taking this unit you may not take 'Recent developments in organic chemistry' as a component of CH30061.
Further information on descriptions Description: Aims:
The aim of the unit is to give students a thorough grounding in the methods, strategies and reagents employed in modern stereoselective organic synthesis.

Learning Outcomes:
After studying this unit students should be able to:
* Analyse the stereochemical course of a variety of reactions
* Describe reagent systems to effect a wide range of simple transformation
* Describe fully the mechanism of these reactions. Apply the information learnt to solve problems
* Critically evaluate publications from the recent literature
* Use examples of recent developments in modern stereoselective organic synthesis.

Skills:
Problem solving (T, F, A)
Scientific writing (F, A), Independent working (f)
Group working (F).

Content:
The unit begins with a section concerned with simple diastereoselection, focusing on the reactions of carbonyl and alkene systems. The concepts of allylic strain and directed reactions are introduced. The use of chiral auxiliaries to control the stereochemistry of organic reactions forms the second section. Particular systems studied include the use of SAMP and RAMP hydrazones and Evans' auxiliaries to control a range of chiral-enolate based bond constructions.
Further information on programme availabilityProgramme availability:

CH40216 is Optional on the following programmes:

Programmes in Natural Sciences
  • UXXX-AFM01 : MSci (hons) Natural Sciences (Full-time) - Year 4
  • UXXX-AKM02 : MSci (hons) Natural Sciences with Professional Placement (Full-time with Thick Sandwich Placement) - Year 5
  • UXXX-AAM02 : MSci (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 5

Notes:
* This unit catalogue is applicable for the 2012/13 academic year only. Students continuing their studies into 2013/14 and beyond should not assume that this unit will be available in future years in the format displayed here for 2012/13.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.