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BB20149: Molecular genetics of vertebrate development

Follow this link for further information on academic years Academic Year: 2013/4
Further information on owning departmentsOwning Department/School: Department of Biology & Biochemistry
Further information on credits Credits: 6
Further information on unit levels Level: Intermediate (FHEQ level 5)
Further information on teaching periods Period: Semester 1
Further information on unit assessment Assessment: EX 80%, PR 20%
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this unit you must take BB10006
Further information on descriptions Description: Aims:
To introduce the study of comparative animal development and to acquaint students with molecular basis and genetics of animal development. The genetic pathways and regulation of gene expression during embryonic development and methods to study these will be covered.

Learning Outcomes:
After taking this course the student should be able to:
* demonstrate a knowledge of the developmental processes across a wide range of species;
* demonstrate an understanding of the genes and pathways regulating development;
* demonstrate a knowledge of the current approaches in the study of gene expression, overexpression and ablation and their relevance to development carry out cytochemical, immunohistochemical and in situ hybridisation procedures.

Learning and studying T/F/A, Written communication T/F/A, Data acquisition, handling and analysis T/F/A, Laboratory skills T/F, Information technology T/F, Problem solving T/F, Information handling & retrieval T/F/A, Working independently T/F.

Animal development covering gametogenesis and fertilisation, early development, mammalian preimplantation development, stem cells, embryonal carcinoma cells, transgenesis and targeted mutagenesis, extraembryonic membranes, X-chromosome inactivation, imprinting, regulation of gene expression, comparative genomics, large scale mutagenesis, cell adhesion, cell movement, morphogenesis and gastrulation.
Laboratory practical sessions covering , cytochemistry, in situ hybridisation and immunohistochemistry of mouse and fish embryos.
Further information on programme availabilityProgramme availability:

BB20149 is Compulsory on the following programmes:

Department of Biology & Biochemistry
  • TSBB-AFM07 : MSc Developmental Biology (Full-time) - Year 1

BB20149 is Optional on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB02 : BSc (hons) Biochemistry (Full-time) - Year 2
  • USBB-AKB06 : BSc (hons) Biochemistry with Professional Placement (Full-time with Thick Sandwich Placement) - Year 2
  • USBB-AFB03 : BSc (hons) Biology (Full-time) - Year 2
  • USBB-AKB07 : BSc (hons) Biology with Professional Placement (Full-time with Thick Sandwich Placement) - Year 2
  • USBB-AFB05 : BSc (hons) Molecular and Cellular Biology (Full-time) - Year 2
  • USBB-AKB08 : BSc (hons) Molecular and Cellular Biology with Professional Placement (Full-time with Thick Sandwich Placement) - Year 2
  • RSBB-AFM14 : Integrated PhD Postgenomic Biosciences (Developmental Biology Route) (Full-time) - Year 1
  • RSBB-AFM08 : Integrated PhD Postgenomic Biosciences (Regenerative Medicine Route) (Full-time) - Year 1
  • TSBB-AFM14 : MRes Developmental Biology (Full-time) - Year 1
  • TXXX-AFM10 : MRes Regenerative Medicine (Full-time) - Year 1

* This unit catalogue is applicable for the 2013/4 academic year only. Students continuing their studies into 2014/15 and beyond should not assume that this unit will be available in future years in the format displayed here for 2013/14.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.