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BB40102: Molecular mechanisms of disease

Follow this link for further information on academic years Academic Year: 2013/4
Further information on owning departmentsOwning Department/School: Department of Biology & Biochemistry
Further information on credits Credits: 6
Further information on unit levels Level: Masters UG & PG (FHEQ level 7)
Further information on teaching periods Period: Semester 1
Further information on unit assessment Assessment: CW 100%
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: In taking this unit you cannot take BB40085 or take BB40118 or take BB40124 and before taking this unit you must take BB20024 and take BB10003 or you must have taken suitable degree units from another University.
Further information on descriptions Description: Aims:
To describe how a defect at the level of the gene results in an observed disease phenotype. To show how such patients can be treated with modern molecular medicine.

Learning Outcomes:
After taking this course the student should be able to:
* explain the common themes of genetic disorders, and how they relate to the overall phenotype;
* explain the principles of tools involved in diagnosis and treatment of the disorders.

Learning and studying T/F/A, Written communication T/F/A, Oral communication T/F/A, Information handling & retrieval T/F/A, Working independently T/F/A.

Diseases: diabetes, glycogen storage diseases, hyperbilirubinaemia, familial hypercholesterolaemia, fibroblast growth factor receptors and skeletal dysplasia.
Diagnosis and treatment: PCR/cloning, antibody engineering, gene therapy, gene targeting in the mouse, mouse models for human disease.
Further information on programme availabilityProgramme availability:

BB40102 is Optional on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB05 : BSc (hons) Molecular and Cellular Biology (Full-time) - Year 3
  • USBB-AKB08 : BSc (hons) Molecular and Cellular Biology with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
  • RSBB-AFM07 : Integrated PhD Postgenomic Biosciences (Biosciences Route) (Full-time) - Year 1
  • RSBB-AFM14 : Integrated PhD Postgenomic Biosciences (Developmental Biology Route) (Full-time) - Year 1
  • RSBB-AFM08 : Integrated PhD Postgenomic Biosciences (Regenerative Medicine Route) (Full-time) - Year 1
  • TSBB-AFM03 : MRes Biosciences (Full-time) - Year 1
  • TSBB-AFM14 : MRes Developmental Biology (Full-time) - Year 1
  • TXXX-AFM10 : MRes Regenerative Medicine (Full-time) - Year 1
  • TSBB-AFM06 : MSc Biosciences (Full-time) - Year 1
  • TSBB-AFM07 : MSc Developmental Biology (Full-time) - Year 1
  • TSBB-AFM05 : MSc Industrial Biotechnology and Enterprise (Full-time) - Year 2
  • TSBB-AFM09 : MSc Medical Biosciences (Full-time) - Year 1

* This unit catalogue is applicable for the 2013/4 academic year only. Students continuing their studies into 2014/15 and beyond should not assume that this unit will be available in future years in the format displayed here for 2013/14.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.