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PA10001: Chemistry of functional groups

Follow this link for further information on academic years Academic Year: 2013/4
Further information on owning departmentsOwning Department/School: Department of Pharmacy & Pharmacology
Further information on credits Credits: 6
Further information on unit levels Level: Certificate (FHEQ level 4)
Further information on teaching periods Period: Semester 1
Further information on unit assessment Assessment: EX 100%
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites:
Further information on descriptions Description: Aims:
To familiarise the student with:
a) the fundamental principles of atomic structure, molecular and intermolecular bonding and functional group recognition,
b) the principles of reaction mechanisms in organic and biochemical systems; to illustrate the importance of 3-d structure in medicinal and biological chemistry.

Learning Outcomes:
At the end of the unit the student should be able to describe the factors that affect the 3-dimensional shape of molecules and assign stereochemical descriptions, present suitable reaction mechanisms for the interconversion of common functional groups and outline how these groups mediate acidity, basicity and weak bonding interactions.

Study skills (T/F); Oral communication (T/F); Working with others (T/F); Problem solving (T/F).

The topics in this unit include atomic structure and hybridisation with its implications for molecular geometry. Intramolecular covalent bonding. Intermolecular weak bonding; origins and relevance to ligand/receptor and substrate/enzyme binding. Structural factors that affect reactivity. Functional groups and their interconversion at a mechanistic level. Stereochemistry in organic and biological molecules. Central role of the carbonyl group in chemistry and biochemistry. The nature of aromaticity and the occurrence and role of aromatic nuclei in drug molecules.
Further information on programme availabilityProgramme availability:

PA10001 is a Designated Essential Unit on the following programmes:

Department of Pharmacy & Pharmacology

PA10001 is Compulsory on the following programmes:

Department of Pharmacy & Pharmacology
  • USPA-AFB02 : BSc (hons) Pharmacology (Full-time) - Year 1
  • USPA-AKB02 : BSc (hons) Pharmacology (Full-time with Thick Sandwich Placement) - Year 1
  • USPA-AKM02 : MPharmacology (hons) (Full-time with Thick Sandwich Placement) - Year 1

* This unit catalogue is applicable for the 2013/4 academic year only. Students continuing their studies into 2014/15 and beyond should not assume that this unit will be available in future years in the format displayed here for 2013/14.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.