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PA40253: Applied pharmacokinetics

Follow this link for further information on academic years Academic Year: 2015/6
Further information on owning departmentsOwning Department/School: Department of Pharmacy & Pharmacology
Further information on credits Credits: 6
Further information on unit levels Level: Masters UG & PG (FHEQ level 7)
Further information on teaching periods Period: Semester 2
Further information on unit assessment Assessment Summary: CW 25%, EX 75%
Further information on unit assessment Assessment Detail:
  • Essay (CW 15%)
  • Moodle Quiz (CW 10%)
  • Examination (EX 75%)
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this module you must take PA10281 AND take PA20294 AND take PA30287
Further information on descriptions Description: Aims:
The aims of this unit are to acquire an understanding of (a) recent advances on therapeutic drug monitoring, (b) variability in ADME processes and (c) individualized drug therapy based on pharmacokinetic, pharmacodynamic and pharmacogenomic principles.

Learning Outcomes:
On successful completion of this unit, the student should be able to: (a) critically evaluate elements of clinical pharmacokinetics and apply them to therapeutic drug monitoring and drug therapy; (b) predict and analyze the effect of variability (disease, genetics, adherence, age etc.) on a therapy outcome and (c) critically analyse and discuss scientific pharmacokinetic data and apply it to drug therapy.

Scientific skills: Data analysis and clinical interpretation. (T/F/A)
Study skills, finding and handling information (T/F/A)
Working with others (F).
Problem solving (T/F/A).
Communication skills (F)

This unit focuses on clinical pharmacokinetics, sources of variability in drug therapy and therapeutic drug monitoring. This will include: (a) the scientific basis for therapeutic drug monitoring and individualized therapy. Application to relevant drugs in practice and recent advances in the field. (b) Variability in the ADME processes caused by disease, age, obesity, interactions, life style and genetics. (c) Use of pharmacokinetics and PK parameters to interpret drug variability and individualize therapy.
Further information on programme availabilityProgramme availability:

PA40253 is Optional on the following programmes:

Department of Pharmacy & Pharmacology
* This unit catalogue is applicable for the 2016/17 academic year only. Students continuing their studies into 2017/18 and beyond should not assume that this unit will be available in future years in the format displayed here for 2016/17.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.