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PA40162: Drug targets in the immune system

Follow this link for further information on academic years Academic Year: 2018/9
Further information on owning departmentsOwning Department/School: Department of Pharmacy & Pharmacology
Further information on credits Credits: 6      [equivalent to 12 CATS credits]
Further information on notional study hours Notional Study Hours: 120
Further information on unit levels Level: Masters UG & PG (FHEQ level 7)
Further information on teaching periods Period:
Semester 2
Further information on unit assessment Assessment Summary: EX 100%
Further information on unit assessment Assessment Detail:
  • Examination (EX 100%)
Further information on supplementary assessment Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites:
Further information on descriptions Description: Aims:
The aims of this unit are to provide a knowledge base of recent developments in understanding the immune system and its role in human diseases, and to examine how such understanding can lead to identification and exploitation of novel drug targets for future therapy.

Learning Outcomes:
On successful completion of this unit, the student should be able to: synthesise an in-depth knowledge of recently identified target molecules and processes in the immune system, evaluate critically the role of these targets in particular therapeutic areas and utilise a range of ICT and cognitive skills in acquiring knowledge and understanding and applying them to complex, incomplete or contradictory situations.

Skills:
Scientific skills (T/F/A)
Study skills, handling information, working with others (T/F)
Problem solving (T/F).

Content:
Following an introduction and brief overview of earlier core units, a number of topics will be discussed using the general formula of molecular target linking to cellular process linking to therapeutic area.. Topics will be selected on the basis of their currency at a given time - examples may include IgE, NF?B, PI-3 kinase, IL-23, P2X7 receptors linking to mast cell degranulation, apoptosis, chemotaxis, inflammation, inflammasome processing linking to respiratory, inflammatory and autoimmune disease states such as allergy, rheumatoid arthritis, asthma.
Further information on programme availabilityProgramme availability:

PA40162 is Optional on the following programmes:

Department of Biology & Biochemistry Department of Pharmacy & Pharmacology Programmes in Natural Sciences
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 5)

Notes: