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CE40126: Advanced biochemical engineering

Follow this link for further information on academic years Academic Year: 2019/0
Further information on owning departmentsOwning Department/School: Department of Chemical Engineering
Further information on credits Credits: 6      [equivalent to 12 CATS credits]
Further information on notional study hours Notional Study Hours: 120
Further information on unit levels Level: Masters UG & PG (FHEQ level 7)
Further information on teaching periods Period:
Semester 1
Further information on unit assessment Assessment Summary: EX 100%
Further information on unit assessment Assessment Detail:
  • Examination (EX 100%)
Further information on supplementary assessment Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites:
Further information on descriptions Description: Aims:
To provide an understanding of the various biological, reactor and separation process strategies that can be employed to produce biochemicals in a controllable and predictable process through the exploitation of bacteria, yeast and higher organisms. To introduce the main unit operations used in the separation of materials of biological origin; to provide an understanding of the role of each operation within a multi-unit process and how this is influenced by the properties of the process stream; to introduce and explore the use of quantitative performance equations for design purposes.

Learning Outcomes:
After successfully completing this unit the student should be aware of the importance of biological considerations when assessing reactor strategies; to be able to assess and design a reactor for cell growth or to carry out an enzyme reaction; to be aware of the main separation techniques available and how their choice is dependent on the nature of the bioproduct to be produced.

Acquisition and critical assessment of technical information in biochemical engineering. Taught, facilitated and assessed.

Oxygen transfer during a fermentation; micro-organism growth kinetics; enzyme reactor kinetics; quantitative performance equations for bioreactor design; strategies for bioreactor equipment design; properties of biochemicals which influence choice and availability of methods; cell recovery; cell disruption/release of intracellular products. General introduction to membrane processes, materials of construction and modes of operation; flux in UF/MF effects of concentration, pressure and temperature; Chromatographic separations, review of techniques available. Design of adsorption columns; simplified models based on equilibrium assumption, kinetic models with and without an assessment of mass transfer coefficients. Prediction of breakthrough.
Further information on programme availabilityProgramme availability:

CE40126 is Compulsory on the following programmes:

Department of Chemical Engineering
  • UECE-AFB05 : BEng(Hons) Chemical Engineering (Year 3)
  • UECE-AKB05 : BEng(Hons) Chemical Engineering with Year long work placement (Year 4)
  • UECE-AFM01 : MEng(Hons) Biochemical Engineering (Year 4)
  • UECE-AKM01 : MEng(Hons) Biochemical Engineering with Year long work placement (Year 5)
  • UECE-AFM05 : MEng(Hons) Chemical Engineering (Year 4)
  • UECE-AKM05 : MEng(Hons) Chemical Engineering with Year long work placement (Year 5)