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BB20027: Infection and immunity II: immunology

Follow this link for further information on academic years Academic Year: 2020/1
Further information on owning departmentsOwning Department/School: Department of Biology & Biochemistry
Further information on credits Credits: 6      [equivalent to 12 CATS credits]
Further information on notional study hours Notional Study Hours: 120
Further information on unit levels Level: Intermediate (FHEQ level 5)
Further information on teaching periods Period: Semester 2
Further information on unit assessment Assessment: CW 20%, EX 80%
Further information on supplementary assessment Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this module you must take BB10005
Further information on descriptions Description: Aims:
To provide the student with a knowledge of animal immune systems, with an emphasis on mammalian systems, including the cellular components of the immune system and how they communicate with one another to generate coherent immune responses. This will be relevant to both infectious disease and non-infectious immunity.
To provide the student with an understanding of how animals defend themselves against invading microorganisms, and how pathogenic microbes overcome these defences. A number of well studied microbial and viral diseases are used as examples. The approach will stress the methods by which knowledge has been gained, and the integrative features of cellular and systemic immunobiology. Lectures are supported by a number of "virtual practicals" that aim to develop interpretative skills.

Learning Outcomes:
After taking this unit, the student will be able to:
* demonstrate knowledge of the topics given in the outline of the course and the ability to integrate such knowledge through answering factual multiple-choice questions on any of these topics, and discussing them in integrative exam questions.
* analyse, display, interpret and draw conclusions from experimental data.

Learning and studying T/F/A, Written Communication T/F/A, Data Acquisition, Handling and Analysis T/F/A, Problem Solving T/F/A, Group Working T/F.

The course is in three parts:
1. Non-specific defences; barriers; skin; innate immunity; secreted antimicrobials; cellular defences; classes of leukocytes; FACS; innate immune responses; phagocytosis; cell killing; acute inflammation; humoral defences, haemostasis; recognition of microbial invaders; immune signalling by cytokines and chemokines, examples of immune evasion and suppression by microbial pathogens.
2. Antibodies and acquired immunity; immunoglobulins, Ig classes; genetic basis of Ab diversity; MHC; T-cell receptors; development of B and T-cells; immunity mediated by B and T cells.
3. The complement system; case studies of interactions between pathogens and the immune system.
Further information on programme availabilityProgramme availability:
NB. Postgraduate programme information will be added when the postgraduate catalogues are published in August 2020

BB20027 is Compulsory on the following programmes:

Department of Biology & Biochemistry
  • UXXX-AFB11 : BSc(Hons) Biomedical Sciences (Year 2)
  • UXXX-AKB11 : BSc(Hons) Biomedical Sciences with Professional Placement (Year 2)

BB20027 is Optional on the following programmes:

Department of Biology & Biochemistry