This 2026 Lancet Commission on liver health in Europe evaluates progress since its 2021 report and finds that liver disease remains a major and growing public health challenge driven largely by preventable risk factors. It shows that cirrhosis and liver cancer together cause about 780 deaths per day in Europe (≈3% of all deaths), with liver cancer mortality rising by more than 50% since 2000, while cirrhosis mortality remains persistently high. The Commission highlights that the burden is closely linked to lifestyle, social inequalities, and commercial determinants (e.g., alcohol and unhealthy diet), and that current policy implementation has been insufficient despite clear evidence on prevention. It concludes that stronger, coordinated policy action could substantially reduce disease burden (potentially nearly halving it), improve life expectancy, and deliver large economic benefits, emphasising prevention, cross-sector policy change, and better implementation of existing recommendations.