BB20220: Genomics 2
[Page last updated: 15 October 2020]
 Academic Year: | 2020/1 |
| Owning Department/School: | Department of Biology & Biochemistry |
| Credits: | 6 [equivalent to 12 CATS credits] |
| Notional Study Hours: | 120 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
- Semester 2
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| Assessment Summary: | CW 20%, EX 80% |
| Assessment Detail: |
- Workshop 1 (CW 10%)
- Workshop 2 (CW 10%)
- Examination (EX 80%)
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| Supplementary Assessment: |
- Like-for-like reassessment (where allowed by programme regulations)
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| Requisites: |
Before taking this module you must take BB10007 OR take BB10214
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| Description: | Aims:
To introduce students to further concepts of genomics relevant to transcriptomics and proteomics.
Learning Outcomes:
After taking this course the student should be able to:
* Explain how whole genome transcriptome information is generated and analysed
* Explain the type of biological information that is contained in genome level gene expression profiles
* Relate gene expression profiles to the basic mechanisms of regulating gene expression
* Explain how gene expression profiling can be used to investigate some disease processes.
Skills:
Knowledge and understanding T/F/A, Intellectual skills F/A, Written communication T/F/A, Numeracy F/A, Data acquisition, handling, and analysis T/F/A, Information technology T/F, Working independently T/F
Content:
Genome wide assessment of gene expression; Comparison of transcriptome data to identify aberrant gene expression patterns of genes and/or pathways in disease states; Comparative genomics combined with transcriptomics to gain insights into the molecular basis of clinically-relevant traits; Proteomics, structural genomics, protein disorder; Gene co-expression and protein-protein networks as means to identify functional interactions among genes; Epigenetics and disease, imprinting and genome-wide assessments of epigenetic markers; Applications of genomics analyses and ethical considerations: Legal applications, pharmacogenomics (diagnostic tools and treatment development), GM crops, etc.
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| Programme availability: |
BB20220 is Optional on the following programmes:
Department of Biology & Biochemistry
- USBB-AFB02 : BSc(Hons) Biochemistry (Year 2)
- USBB-AKB06 : BSc(Hons) Biochemistry with Professional Placement (Year 2)
- USBB-AFB03 : BSc(Hons) Biology (Year 2)
- USBB-AKB07 : BSc(Hons) Biology with Professional Placement (Year 2)
- UXXX-AFB11 : BSc(Hons) Biomedical Sciences (Year 2)
- UXXX-AKB11 : BSc(Hons) Biomedical Sciences with Professional Placement (Year 2)
Programmes in Natural Sciences
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Physics stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Physics stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Physics stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Physics with Biology stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Physics with Biology stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Physics with Biology stream) with Year long work placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Physics stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Physics stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Physics stream) with Professional Placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Professional Placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Physics with Biology stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Physics with Biology stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Physics with Biology stream) with Professional Placement (Year 2)
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Notes: - This unit catalogue is applicable for the 2020/21 academic year only. Students continuing their studies into 2021/22 and beyond should not assume that this unit will be available in future years in the format displayed here for 2020/21.
- Programmes and units are subject to change in accordance with normal University procedures.
- Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
- Find out more about these and other important University terms and conditions here.
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