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CH30211: Chemistry beyond the molecule

[Page last updated: 20 April 2021]

Academic Year: 2021/2
Owning Department/School: Department of Chemistry
Credits: 3      [equivalent to 6 CATS credits]
Notional Study Hours: 60
Level: Honours (FHEQ level 6)
Period:
Semester 2
Assessment Summary: CW 30%, EX 70%
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites: Before taking this module you must take CH20149 OR take CH20150 . This unit is not available to students on placement or study abroad programmes.
Aims: To teach aspects of supramolecular chemistry with an emphasis on (bio)chemical recognition and sensing.

Learning Outcomes: After taking this course the student should be able to:
* Identify and discriminate the relevant supramolecular interactions based on the solvent system;
* Describe analytical techniques used to investigate supramolecular interactions;
* Understand the role of solvation in molecular recognition and chemical reactivity;
* Describe dynamic combinatorial chemistry;
* Explain the enthalpic and entropic contributions in molecular recognition;
* Identify and describe different types of sensors;
* Design basic on/off and off/on molecular sensors;
* Explain the difference between sensing and sequestering;
* Describe molecular carriers and cellular channels and their mode of action.

Skills: Learning and studying T/F/A, Written communication T/F/A, Numeracy & computation T/F/A, Problem solving T/F, Information handling & retrieval T/F/A, Working independently T/F, Career preparation T/F.

Content: Supramolecular Chemistry: Concepts and definition; Classification of supramolecular interactions; Cooperativity, effective molarity and chelate effect; Highlights of supramolecular interactions in nature. Solvation and solvophobic effects. Characterisation of supramolecular systems. Supramolecular chemistry through design: Small molecule receptors; Small molecule guests for biological targets; Supramolecular polymers. Dynamic combinatorial chemistry: Types of reversible chemistry; Analytical methods. Solution Host-Guest Chemistry: Cation receptors; Anion receptors; Neutral molecule receptors; Ditopic receptors. Sensors. Natural and artificial channels.

Programme availability:
NB. Postgraduate programme information will be added when the postgraduate catalogues are published in August 2021

CH30211 is Optional on the following programmes:

Department of Chemistry
  • USCH-AFB01 : BSc(Hons) Chemistry (Year 3)
  • USCH-AAB02 : BSc(Hons) Chemistry with Study year abroad (Year 4)
  • USCH-AFB07 : BSc(Hons) Chemistry for Drug Discovery (Year 3)
  • USCH-AAB08 : BSc(Hons) Chemistry for Drug Discovery with Study year abroad (Year 4)
  • USCH-AKB08 : BSc(Hons) Chemistry for Drug Discovery with Industrial Placement (Year 4)
  • USCH-AKB02 : BSc(Hons) Chemistry with Industrial Placement (Year 4)
  • USCH-AFB03 : BSc(Hons) Chemistry with Management (Year 3)
  • USCH-AAB04 : BSc(Hons) Chemistry with Management with Study year abroad (Year 4)
  • USCH-AKB04 : BSc(Hons) Chemistry with Management with Industrial Placement (Year 4)
  • USCH-AFM02 : MChem(Hons) Chemistry (Year 3)
  • USCH-AFM05 : MChem(Hons) Chemistry for Drug Discovery (Year 3)
  • USCH-AFM07 : MSci(Hons) Chemistry with Management (Year 3)
  • USCH-AKM07 : MSci(Hons) Chemistry with Management with Industrial Placement (Year 4)
Programmes in Natural Sciences
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Professional Placement (Year 4)

Notes:

  • This unit catalogue is applicable for the 2021/22 academic year only. Students continuing their studies into 2022/23 and beyond should not assume that this unit will be available in future years in the format displayed here for 2021/22.
  • Programmes and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.