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CH20176: Organic chemistry 3 for visiting students

[Page last updated: 05 August 2021]

Academic Year: 2021/2
Owning Department/School: Department of Chemistry
Credits: 6 [equivalent to 12 CATS credits]
Notional Study Hours: 120
Level: Intermediate (FHEQ level 5)
Period:
Semester 1
Assessment Summary: EX 100%
Assessment Detail:
  • Examination (EX 100%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites: In taking this module you cannot take CH20149 OR take CH20150
Aims: To provide the student with a working knowledge of important classes of organic transformations give an overview of retrosynthetic analysis as a valuable method for the design of an organic molecule.

Learning Outcomes: After studying this Unit, students should be able to:
* interpret and predict NMR spectra and mass spectra;
* account for the importance of stereoselectivity in organic synthesis;
* demonstrate the important relationship between structure and reactivity for organic molecules;
* design syntheses of heterocyclic and alicyclic compounds from common starting materials apply retrosynthesis methods to a selected range of compounds.

Skills: Problem solving (T, F, A), Data Analysis (T, F, A), Independent working (F), Group working (F).

Content: Interpretation of NMR spectra including homotopic and diastereotopic protons. Correlation spectroscopy. Mass spectrometry.
The principles of retrosynthesis. The use of carbon nucleophiles in retrosynthesis. Malonate ester synthesis and applications. Umpolung reagents. Alkene synthesis, including Wittig reaction. Oxidation reactions of alkenes and alcohols. Reduction reactions of ketones and other carbonyl compounds. Review of aromatic chemistry. Description, reactivity and synthesis of heterocycles including pyrroles, furan, thiophene, pyridine and indoles. Synthesis and reactivity of naphthalene, quinolines and isoquinolines. Concepts of organopalladium chemistry. Concepts of combinatorial chemistry for the synthesis of libraries of heterocycles.

Further information on programme availabilityProgramme availability:

CH20176 is only available to visiting/exchange students


Notes:

  • This unit catalogue is applicable for the 2021/22 academic year only. Students continuing their studies into 2022/23 and beyond should not assume that this unit will be available in future years in the format displayed here for 2021/22.
  • Programmes and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.