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Medical and Industrial Biotechnology

Our research focuses on a fundamental understanding of the molecular processes of life, especially those involved in health and disease.

Project status

In progress



3 protein structures with different colours
Crystal structure of two knob domains, isolated from cow antibodies in complex with complement C5, a drug target for inflammatory diseases, including severe COVID-19

The theme tackles fundamental and applied questions to deliver advances in medical and industrial biotechnology.

Our research ranges from fundamental properties of biomolecules to molecular and metabolic engineering, novel detection and diagnosis methodologies, and therapeutic discovery and design.

The theme develops new products and solutions that we seek to apply, through collaboration and direct commercialisation.

Expertise in the theme includes:

  • chemical, molecular, structural and synthetic biology
  • enzymology
  • biophysics
  • metabolic engineering
  • cell culture in stirred tank and photo-bioreactors
  • X-ray crystallography
  • nuclear magnetic resonance
  • structure-based drug design

We have strong links with other Departments within the University, including Chemistry, Pharmacy & Pharmacology and Physics within the Faculty of Science, and Chemical Engineering and Electronic & Electrical Engineering within the Faculty of Engineering & Design. We also have substantial industrial collaborations.

Members of the theme are affiliated with the Centre for Biosensors, Bioelectronics and Biodevices (C3Bio), Centre for Integrated Bioprocessing Research (CIBR), Centre for Nanoscience and Nanotechnology (CNAN), Centre for Sustainable & Circular Technologies (CSCT), Centre for Therapeutic Innovation (CTI), and Cancer Research at Bath (CR@B) at the University.

Research areas include:

  • biomolecular structure, dynamics and interactions
  • enzyme stability, catalysis, metabolism and engineering
  • biosensing, diagnostics and vaccine development
  • metabolic engineering and synthetic biology
  • peptide library screening for therapeutic discovery
  • inflammation
  • diseases: autoimmune, infectious, neurodegenerative, cancers


There are opportunities for postgraduate research throughout our group. Interested students are encouraged to contact academic staff directly or check our PhD projects on

Find out more about studying for a postgraduate degree at Bath.


Read about our other research themes

Find out more about research in the Department of Biology & Biochemistry.


If you have any questions about our research activity please contact us - details below: