Drug and target discovery
We deliver innovative drug and target discovery science to address to priority health and medical problems.
Our strength lies in the diversity and breadth of our experience from drug discovery and the understanding of fundamental properties of cells through to target validation and evaluating the mechanisms of disease.
We have combined inter-disciplinary expertise in drug design and chemical synthesis through to models of cell behaviour and disease.
Specific areas of research expertise include:
- Inflammation, infection and immunity including musculoskeletal and respiratory disease
- Neuroscience including depression, addiction, epilepsy, and learning and memory
- Cancer with a particular focus on prostate cancer
- Cardiovascular science pharmacology
We are committed to the training of future research leaders in drug and target discovery. Our dynamic research environment aims to generate the next generation of highly skilled researchers.
Impact case stories
New tool for testing drugs for prostate cancer
We have developed an innovative tool to test potential drugs for prostate cancer. This research was funded by Prostate Cancer UK with support from the Movember Foundation. We hope this technique will help speed up the development of new treatments for the disease, the most common form of cancer in men in the UK.
Using daffodils to create cancer treatments
We're exploring how compounds derived from natural products found in daffodils could be used in potential cancer treatments.
Understanding the immune response
We have made a breakthrough in identifying the genes that regulate the immune response. Using the latest DNA sequencing technology, the team has discovered a family of genes that do this called long non-coding RNAs – a chemical structure similar to DNA. This discovery has the potential to provide a new approach to treating many diseases.